Porphyria is a disease related to groups of disorder that affected to nervous systems or skin. The most common problems of all phorphyria are the body cumulated porphyrins or porphyrin precursors, these chemicals are usually not cumulated. In general, depending on what type of phorphyria will build up what’s chemical.
The Symptoms of Phorphyria
Buring
Blister
Scar of sun expose
Pain in the back, arms and legs
Redish color in urine or/and urine retention
Nausea
Vomiting
Confusion, hallucinations and seizures
Constipation
Muscle weakness
Liver function abnormalities.
The Causes of Phorphyria
There are about 8 types of phorphyria, and the causes will be different for each type.
Acute Intermittent Porphyria (AIP): caused by The deficient enzyme is porphobilinogen deaminase (PBGD), also known as hydroxymethylbilane synthase. These are others factors may be activating the problems such as change in hormones, drugs, and diets.
Congenital Erythropoietic Porphyria (CEP): caused by deficiency of uroporphyrinogen III cosynthase. Porphyrins are increased significantly in bone marrow, red blood cells, plasma, urine, feces, the teeth and bones. Most of the problems occur during infancy.
Porphyria Cutanea Tarda (PCT): Caused by deficiency of uroporphyrinogen decarboxylase (UROD). Most people have this problems show no symptoms, but when disease are triggered by these factors such as iron, alcohol, hepatitis C virus (HCV), HIV, estrogens, PCT will be active. Porphyrine will build up Large amounts of porphyrins in the liver.
ALAD Porphyria (ADP): caused by deficiency of the enzyme delta-aminolevulinic acid dehydratase (ALAD). This disease is very rare.
Hepatoerythropoietic Porphyria (HEP): Caused by deficiency of uroporphyrinogen decarboxylase. Porphyrins build up in liver, plasma, urine, feces, in bone marrow and red blood cells.
Hereditary Coproporphyria (HCP): caused by deficiency of coproporphyrinogen oxidase.
Variegate Porphyria (VP): caused by deficiency of protoporphyrinogen oxidase.
Erythropoietic Protoporphyria (EPP) or Protoporphyria: caused by abnormally elevated levels of protoporphyrin IX in erythrocytes (red blood cells), feces and plasma (the fluid portion of circulating blood). The porphyrins build up in bone marrow, red blood cells and sometimes the liver.
The Treatment of phorphyria
The best treatment will be consulted by your physician to decide what the main cause of the disease is. Here some of the options are available.
Patient with EPP: should avoid sunlight according to their personal sensitivity. Taking some products that contain Lumitene/Beta-Carotene for treatment, it can be found in green plant. Access of vitamins A and D can cause serious health issues. the patient should consume the foods are rich iron such as red meat, spinach, baked potato with skin, red kidney beans, raisins, etc.
Patient with AIP: most of the patient is attacked by low intake of glucose and carbohydrates with weight loss purpose. Medication for pain, nausea and vomiting are needed. A high intake of glucose or other carbohydrates are recommended.
Patient with CEP: removing the spleen, blood transfusion, Bone Marrow Transplantation may reduce the porphyrines. In some case, taking Activated charcoal by mouth will help as well.
Patient with PCT: repeated a schedule to the removal of blood (phlebotomies) to reduce amount of iron in the liver.
Folliculitis is skin conditions as the presence of inflammatory cells. Folliculitis basically is infection of hair follicles, it may appear anywhere on your skin or scalp. It causes by the formation of a pustule or inflammatory of the nodule surrounding your hair. The inflammation may be either limited to the superficial aspect of the follicle with primary involvement of the infundibulum or the inflammation can affect both the superficial and deep aspects. In severe cases may cause permanent hair loss and scarring, and even mild folliculitis can make you feel uncomfortable and embarrassing. Folliculitis may occur as your hairs regrow after shaving, waxing, electrolysis or plucking. Swabs taken from the pustules are sterile i.e. there is no growth of bacteria or other organisms.
Follioculitis usually caused by bacteria. The most common form of infectious folliculitis is known as barbers itch or impetigo of Bockhart, and these usually caused by Staphylococcus aureus. Yeast and another type of fungus can also others cause. Folliculitis caused by a fungus is seen the most in people who got trouble with fighting infections because they have an impaired immune system. Tars are also another forms of folliculitis which are non-infectious, when oils and greases that come into contact with your skin. The most of the lesions are seen in your bearded area, often occur on the upper lip near by the nose, as erythematous follicular-based papules or pustules that can rupture and leave a yellow crust. The pustule is often pierced by a hair that is easily extracted from the follicle. This form of folliculitis may occur more commonly in staphylococcal nasal carriers.
Causes of Folliculitis
Saving friction.
trauma.
Excessive perspiration.
Occlusion.
Inflammatory skin conditions.
Bacterial and Fungal
Viral
Parasite
Symptoms of Folliculitis
Pain.
Red and inflammation of the skin
Edema.
Yellow pus-filled lesions.
Small pimples or acne.
Treatment of Folliculitis
there is no requirement treatment forHot tub folliculitis, although doctors may prescribe some medication such as an oral or topical to help relieve itching. If the patient has been taken immunocompromised or the lesions are persistent oral ciprofloxacin. Topical antibiotics, such as bacitracin with polymyxin B, may be given. Fusidic acid is also available both as a cream and as an ointment. You should apply it thinly on to the infected area 3-4 times daily. Mupirocin is available both as a cream and an ointment as well. You may want to apply it thinly on the affected area 3 times a day for up to at lease 10 days. It may be used on all ages except for in the US, the Bactroban nasal ointment is not recommended applying to children under the age of 12. Eosinophilic folliculitis therapies are also very effective against eosinophilic folliculitis, but topical corticosteroids are often another choice of treatment. Applying moist heat compresses to the local area helps promote vasodilation (dilation of the blood vessels) and drainage from the lesions. Keeping skin clean, dry, and free from abrasions or irritation will help to prevent folliculitis. isotretinoin (Accutane) has been used treat severe cases, sometimes it take several months to cure the problems.
Urticaria also called hives or nettle rash is skin condition that cause by allergic reaction due to foods, drugs, and others allergen due environments and emotional etc. Hives could last for several of hours to 5-6 weeks. Hives may appear on your face, lips, tongue, throat, arms, legs and ears.
Causes of Urticaria
Sea foods like shellfish such as mussels, crabs, etc. could cause serious hives
Medicines such as Aspirin or Penicillin could be the reason to get urticaria (hives).
Fruit such as strawberry also cause allergic.
Drinking alcohol also has more change of getting hives.
Emotional stress is one of the reasons to get urticaria.
Reaction to cold or hot water
Reaction to wear bra-straps, panty or thong bands, belts for long periods of time.
Symptoms of Urticaria
• Rash and swelling
• Itching
Treatment of urticaria
Taking cold shower will relieve hives
Taking antihistamines medicines such as hydroxyzine, cetirizine will help for hives attacks.
Lacitrex is natural effective treatment for hives.
Manage stress by doing yoga and meditation will be helpful.
Further treatment on skin disease such as Tungiasis
Tungisis is skin disease that caused infection by the parasites known as Sand flea, Chigoe flea, Jigger, Pico, and Nigua. They were found in carpet, rugs, funitures, vehicles, lawn and yards. Fleas needed to warm blood to host such as human, cattle, sheep, horses, mules, rats, mice, dogs, pigs, and other wild animals.
Symptoms of Tungiasis
Itching
Pain
Inflammation
Lession, pump or nodes
Ulcer, blister
Lose of toes or toe nails.
If untreated with severe infestation, ulceration and fibrosis could cause bacteremia, Lymphangitis, tetanus, ainhum and gangrene.
Treatment of Tungiasis
Surgical extraction, using sterile needle to extract the whole flea, be sure get entire the flea out, if the flea is torn or some parts of the flea left in the skin, severe inflammation will occur. This method is the best method to treat Tungiasis.
Applying topical ointments or lotions on the affected area such as Ivermectin, Thiabendazole, Metrifonate.
In Chinese herb medicine, they are always using the heat and cold in the blood, so what’s that mean is the foods we eat carrying some element that in Western medicines never explain. These are factors that can helps to you understanding what the cause of skin problems is.
Too much of deep fried, greasy, and spicy foods
Not enough sleep or going to bed too late
Too much shellfish such as crabs, claim or mussels, etc.
If you really care for your skin and the products that you are using every day, the best way to understand what’s it all about. This video clips will review to you. The science research with the process of skin healing and the key ingredients of vitamins, minerals, plant extracts such as Alpha and Beta hyproxy acids, antioxidants in green tea and peptides.
